5K2A

2.5 angstrom A2a adenosine receptor structure with sulfur SAD phasing using XFEL data

Summary for 5K2A

Entry DOI	10.2210/pdb5k2a/pdb
Related	5K2B 5K2C 5K2D
Descriptor	Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ... (8 entities in total)
Functional Keywords	a2a adenosine receptor, membrane protein, gpcr, structural genomics, psi-biology, gpcr network
Biological source	Homo sapiens, Escherichia coli (Human)
Total number of polymer chains	1
Total formula weight	57990.70
Authors	Batyuk, A.,Galli, L.,Ishchenko, A.,Han, G.W.,Gati, C.,Popov, P.,Lee, M.-Y.,Stauch, B.,White, T.A.,Barty, A.,Aquila, A.,Hunter, M.S.,Liang, M.,Boutet, S.,Pu, M.,Liu, Z.-J.,Nelson, G.,James, D.,Li, C.,Zhao, Y.,Spence, J.C.H.,Liu, W.,Fromme, P.,Katritch, V.,Weierstall, U.,Stevens, R.C.,Cherezov, V.,GPCR Network (GPCR) (deposition date: 2016-05-18, release date: 2016-09-21, Last modification date: 2018-11-28)
Primary citation	Batyuk, A.,Galli, L.,Ishchenko, A.,Han, G.W.,Gati, C.,Popov, P.A.,Lee, M.Y.,Stauch, B.,White, T.A.,Barty, A.,Aquila, A.,Hunter, M.S.,Liang, M.,Boutet, S.,Pu, M.,Liu, Z.J.,Nelson, G.,James, D.,Li, C.,Zhao, Y.,Spence, J.C.,Liu, W.,Fromme, P.,Katritch, V.,Weierstall, U.,Stevens, R.C.,Cherezov, V. Native phasing of x-ray free-electron laser data for a G protein-coupled receptor. Sci Adv, 2:e1600292-e1600292, 2016 Cited by PubMed: 27679816 DOI: 10.1126/sciadv.1600292 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation