5K10
Cryo-EM structure of isocitrate dehydrogenase (IDH1)
Summary for 5K10
| Entry DOI | 10.2210/pdb5k10/pdb |
| Related | 5K0Z 5K11 5K12 |
| EMDB information | 8191 8192 8193 8194 |
| Descriptor | Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (2 entities in total) |
| Functional Keywords | isocitrate dehydrogenase, small metabolic complex, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 94160.33 |
| Authors | Merk, A.,Bartesaghi, A.,Banerjee, S.,Falconieri, V.,Rao, P.,Earl, L.,Milne, J.,Subramaniam, S. (deposition date: 2016-05-17, release date: 2016-06-08, Last modification date: 2024-03-06) |
| Primary citation | Merk, A.,Bartesaghi, A.,Banerjee, S.,Falconieri, V.,Rao, P.,Davis, M.I.,Pragani, R.,Boxer, M.B.,Earl, L.A.,Milne, J.L.,Subramaniam, S. Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery. Cell, 165:1698-1707, 2016 Cited by PubMed: 27238019DOI: 10.1016/j.cell.2016.05.040 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report
