5JZX

Crystal Structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Mycobacterium tuberculosis

Summary for 5JZX

Entry DOI	10.2210/pdb5jzx/pdb
Descriptor	UDP-N-acetylenolpyruvoylglucosamine reductase, FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, ... (4 entities in total)
Functional Keywords	reductase, peptidoglycan synthesis, nadph oxidation, rossmann fold, oxidoreductase
Biological source	Mycobacterium tuberculosis H37Rv
Cellular location	Cytoplasm : P9WJL9
Total number of polymer chains	6
Total formula weight	259201.22
Authors	Dharavath, S.,Eniyan, K.,Bajpai, U.,Gourinath, S. (deposition date: 2016-05-17, release date: 2017-05-10, Last modification date: 2023-11-08)
Primary citation	Eniyan, K.,Dharavath, S.,Vijayan, R.,Bajpai, U.,Gourinath, S. Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis Biochim. Biophys. Acta, 1866:397-406, 2017 Cited by PubMed: 29203374 DOI: 10.1016/j.bbapap.2017.11.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation