5JXA
Crystal structure of ligand-free VRC03 antigen-binding fragment.
Summary for 5JXA
Entry DOI | 10.2210/pdb5jxa/pdb |
Descriptor | VRC03 Heavy chain, VRC03 Light chain, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | hiv-1, cd4 binding site, neutralizing, antibody development, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 49259.15 |
Authors | Zhou, T.,Moquin, S.,Joyce, M.G.,Mascola, J.R.,Kwong, P.D. (deposition date: 2016-05-12, release date: 2016-07-27, Last modification date: 2023-09-27) |
Primary citation | Davenport, T.M.,Gorman, J.,Joyce, M.G.,Zhou, T.,Soto, C.,Guttman, M.,Moquin, S.,Yang, Y.,Zhang, B.,Doria-Rose, N.A.,Hu, S.L.,Mascola, J.R.,Kwong, P.D.,Lee, K.K. Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies. Structure, 24:1346-1357, 2016 Cited by PubMed: 27477385DOI: 10.1016/j.str.2016.06.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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