5JUL

Near atomic structure of the Dark apoptosome

This is a large structure.

Summary for 5JUL

EMDB information8177
DescriptorApaf-1 related killer DARK, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE (2 entities in total)
Functional Keywordsdark, apoptosome, apotosis, aaa+ atpase, apoptosis
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains16
Total molecular weight2665954.91
Authors
Cheng, T.C.,Akey, I.V.,Yuan, S.,Yu, Z.,Ludtke, S.J.,Akey, C.W. (deposition date: 2016-05-10, release date: 2017-02-22, Last modification date: 2018-07-18)
Primary citation
Cheng, T.C.,Akey, I.V.,Yuan, S.,Yu, Z.,Ludtke, S.J.,Akey, C.W.
A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation.
Structure, 25:40-52, 2017
PubMed: 27916517 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2016.11.002
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers332.6%0.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 5jul
no rotation
Molmil generated image of 5jul
rotated about x axis by 90°
Molmil generated image of 5jul
rotated about y axis by 90°