Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis in complex with Mn2+, uridine-diphosphate (UDP) and glucosyl-3-phosphoglycerate (GPG) - GpgS*GPG*UDP*Mn2+_2

Summary for 5JUC

DescriptorGlucosyl-3-phosphoglycerate synthase, URIDINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywordstransferase
Biological sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains1
Total molecular weight35614.99
Albesa-Jove, D.,Sancho-Vaello, E.,Rodrigo-Unzueta, A.,Comino, N.,Carreras-Gonzalez, A.,Arrasate, P.,Urresti, S.,Guerin, M.E. (deposition date: 2016-05-10, release date: 2017-05-24, Last modification date: 2018-12-05)
Primary citation
Albesa-Jove, D.,Romero-Garcia, J.,Sancho-Vaello, E.,Contreras, F.X.,Rodrigo-Unzueta, A.,Comino, N.,Carreras-Gonzalez, A.,Arrasate, P.,Urresti, S.,Biarnes, X.,Planas, A.,Guerin, M.E.
Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Structure, 25:1034-1044.e3, 2017
PubMed: 28625787 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2017.05.009
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20720 1.3% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload