5JSV

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-((((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)amino)-1H-imidazo[4,5-g]quinazolin-8(7H)-one

Summary for 5JSV

• Entry DOI: 10.2210/pdb5jsv/pdb
• Related: 1P0D 4KWO 4LBU 4LEQ 4PUK 5I07
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: co-crystallization, carbohydrates, transferase, transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821
• Total number of polymer chains: 1
• Total formula weight: 43705.25

Authors

Ehrmann, F.R.,Nguyen, D.,Heine, A.,Klebe, G. (deposition date: 2016-05-09, release date: 2017-05-24, Last modification date: 2024-01-10)

• Primary citation: Ehrmann, F.R.,Schaefer, E.,Heine, A.,Diederich, F.,Klebe, G.; Application of carbohydrates based lin-benzoguanines in a solvent-exposed subpocket of the tRNA-modifying Enzyme TGT; To be Published,

Experimental method

X-RAY DIFFRACTION (1.17 Å)