5JQ3
Crystal structure of Ebola glycoprotein
Summary for 5JQ3
Entry DOI | 10.2210/pdb5jq3/pdb |
Descriptor | Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, Envelope glycoprotein 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | ebola virus, filoviridae, envelope glycoprotein, protein inhibitor complex, ibuprofen, toremifene, viral protein |
Biological source | Ebola virus - Mayinga, Zaire, 1976 More |
Cellular location | GP2: Virion membrane ; Single-pass type I membrane protein . GP1: Virion membrane ; Peripheral membrane protein. GP2-delta: Secreted : Q05320 |
Total number of polymer chains | 2 |
Total formula weight | 57663.37 |
Authors | Zhao, Y.,Ren, J.,Stuart, D.I. (deposition date: 2016-05-04, release date: 2016-06-29, Last modification date: 2024-01-10) |
Primary citation | Zhao, Y.,Ren, J.,Harlos, K.,Jones, D.M.,Zeltina, A.,Bowden, T.A.,Padilla-Parra, S.,Fry, E.E.,Stuart, D.I. Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature, 535:168-172, 2016 Cited by PubMed: 27362232DOI: 10.1038/nature18615 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
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