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5JOR

Crystal structure of unbound anti-glycan antibody Fab14.22 at 2.2 A

Summary for 5JOR
Entry DOI10.2210/pdb5jor/pdb
Related5JOP
DescriptorFab14.22 heavy chain, Fab 14.22 light chain, GLYCEROL, ... (6 entities in total)
Functional Keywordss. pneumoniae serotype 14, anti-glycan b cells, synthetic conjugate vaccine, nanomolar affinity anti-glycan antibody, immune system, immune system-bacterial glycan complex
Biological sourceMus musculus
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Total number of polymer chains8
Total formula weight213295.69
Authors
Sarkar, A.,Irimia, A.,Teyton, L.,Wilson, I.A. (deposition date: 2016-05-02, release date: 2017-03-22, Last modification date: 2023-09-27)
Primary citationPolonskaya, Z.,Deng, S.,Sarkar, A.,Kain, L.,Comellas-Aragones, M.,McKay, C.S.,Kaczanowska, K.,Holt, M.,McBride, R.,Palomo, V.,Self, K.M.,Taylor, S.,Irimia, A.,Mehta, S.R.,Dan, J.M.,Brigger, M.,Crotty, S.,Schoenberger, S.P.,Paulson, J.C.,Wilson, I.A.,Savage, P.B.,Finn, M.G.,Teyton, L.
T cells control the generation of nanomolar-affinity anti-glycan antibodies.
J. Clin. Invest., 127:1491-1504, 2017
Cited by
PubMed: 28287405
DOI: 10.1172/JCI91192
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.206 Å)
Structure validation

217705

數據於2024-03-27公開中

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