5JMY

NEPRILYSIN COMPLEXED WITH LBQ657

5JMY の概要

• エントリーDOI: 10.2210/pdb5jmy/pdb
• 分子名称: Neprilysin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: hydrolase, lbq657, sacubitril, heart failure
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 162585.10

構造登録者

Schiering, N.,Wiesmann, C. (登録日: 2016-04-29, 公開日: 2016-06-15, 最終更新日: 2024-01-10)

• 主引用文献: Schiering, N.,D'Arcy, A.,Villard, F.,Ramage, P.,Logel, C.,Cumin, F.,Ksander, G.M.,Wiesmann, C.,Karki, R.G.,Mogi, M.; Structure of neprilysin in complex with the active metabolite of sacubitril.; Sci Rep, 6:27909-27909, 2016; PubMed: 27302413; DOI: 10.1038/srep27909

実験手法

X-RAY DIFFRACTION (2 Å)