5JLG

The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and compound I, a piano-stool organometallic Ru(II) arene compound containing an O,S-chelating ligand

5JLG の概要

• エントリーDOI: 10.2210/pdb5jlg/pdb
• 分子名称: Ribonuclease pancreatic, RUTHENIUM ION, methyl (2Z)-3-hydroxy-3-(3-hydroxyphenyl)prop-2-ene(dithioate), ... (5 entities in total)
• 機能のキーワード: ruthenated protein, protein-ru compound adducts, hydrolase, piano-stool organometallic ru(ii) arene compounds
• 由来する生物種: Bos taurus (Cattle)
• 細胞内の位置: Secreted: P61823
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28305.82

構造登録者

Ferraro, G.,Merlino, A. (登録日: 2016-04-27, 公開日: 2016-08-03, 最終更新日: 2024-01-10)

• 主引用文献: Hildebrandt, J.,Gorls, H.,Hafner, N.,Ferraro, G.,Durst, M.,Runnebaum, I.B.,Weigand, W.,Merlino, A.; Unusual mode of protein binding by a cytotoxic pi-arene ruthenium(ii) piano-stool compound containing an O,S-chelating ligand.; Dalton Trans, 45:12283-12287, 2016; PubMed: 27427335; DOI: 10.1039/c6dt02380k

実験手法

X-RAY DIFFRACTION (1.79 Å)