5JL9

HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #4

Summary for 5JL9

Related3EQM 3S79 5JKV 5JKW 5JL6 5JL7
DescriptorAromatase, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ... (4 entities in total)
Functional Keywordsaromatase, cytochrome p450, human placenta, estrogen synthase, androstenedione, oxidoreductase
Biological sourceHomo sapiens (Human)
Cellular locationMembrane; Peripheral membrane protein P11511
Total number of polymer chains1
Total molecular weight58857.76
Authors
Ghosh, D.,Lo, J.,Egbuta, C. (deposition date: 2016-04-26, release date: 2017-04-26, Last modification date: 2018-05-30)
Primary citation
Ghosh, D.,Egbuta, C.,Lo, J.
Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
PubMed: 29476820 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsbmb.2018.02.009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21030.9%6.7%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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