5JJS
Dengue 3 NS5 protein with compound 27
Summary for 5JJS
Entry DOI | 10.2210/pdb5jjs/pdb |
Related | 5JJR |
Descriptor | Genome polyprotein, ZINC ION, DI(HYDROXYETHYL)ETHER, ... (8 entities in total) |
Functional Keywords | rdrp, dengue, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Dengue virus 3 |
Cellular location | Virion membrane ; Multi-pass membrane protein : Q6DLV0 |
Total number of polymer chains | 1 |
Total formula weight | 104846.85 |
Authors | Lescar, J.,El Sahili, A. (deposition date: 2016-04-25, release date: 2016-07-06, Last modification date: 2023-11-08) |
Primary citation | Lim, S.P.,Noble, C.G.,Seh, C.C.,Soh, T.S.,El Sahili, A.,Chan, G.K.,Lescar, J.,Arora, R.,Benson, T.,Nilar, S.,Manjunatha, U.,Wan, K.F.,Dong, H.,Xie, X.,Shi, P.Y.,Yokokawa, F. Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling Plos Pathog., 12:e1005737-e1005737, 2016 Cited by PubMed: 27500641DOI: 10.1371/journal.ppat.1005737 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report