5JGO

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with allyl (2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-6-yl)carbamate

5JGO の概要

• エントリーDOI: 10.2210/pdb5jgo/pdb
• 関連するPDBエントリー: 1P0D 3S1G 4KWO 4PUK 5I07
• 分子名称: Queuine tRNA-ribosyltransferase, allyl (2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-6-yl)carbamate, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: co-crystallization, shigellosis, prodrugs, transferase, transferase inhibitor
• 由来する生物種: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43613.74

構造登録者

Ehrmann, F.R.,Heine, A.,Klebe, G. (登録日: 2016-04-20, 公開日: 2017-05-10, 最終更新日: 2024-01-10)

• 主引用文献: Ehrmann, F.R.,Hohn, C.,Heine, A.,Reuter, K.,Diederich, F.,Klebe, G.; Carbamate-protected lin-Benzoguanines as promising candidates for improving solubility and membrane permeability; To be published,

実験手法

X-RAY DIFFRACTION (1.37 Å)