5JF7

Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor SMP289

5JF7 の概要

• エントリーDOI: 10.2210/pdb5jf7/pdb
• 分子名称: Peptide deformylase, 2-(3-benzyl-5-bromo-1H-indol-1-yl)-N-hydroxyacetamide, ACETATE ION, ... (6 entities in total)
• 機能のキーワード: pdf, type 2, nme, n-terminal methionine excision, streptococcus agalactiae, inhibitor, smp289, hydrolase
• 由来する生物種: Streptococcus agalactiae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23970.32

構造登録者

Fieulaine, S.,Giglione, C.,Meinnel, T.,Hamiche, K. (登録日: 2016-04-19, 公開日: 2016-11-30, 最終更新日: 2024-01-10)

• 主引用文献: Fieulaine, S.,Alves de Sousa, R.,Maigre, L.,Hamiche, K.,Alimi, M.,Bolla, J.M.,Taleb, A.,Denis, A.,Pages, J.M.,Artaud, I.,Meinnel, T.,Giglione, C.; A unique peptide deformylase platform to rationally design and challenge novel active compounds.; Sci Rep, 6:35429-35429, 2016; PubMed: 27762275; DOI: 10.1038/srep35429

実験手法

X-RAY DIFFRACTION (2.1 Å)