5JCW

Crystal Structure of hGSTP1-1 with Glutathione Adduct of Phenethyl Isothiocyanate

Summary for 5JCW

• Entry DOI: 10.2210/pdb5jcw/pdb
• Related: 5JCU
• Descriptor: Glutathione S-transferase P, L-gamma-glutamyl-S-[(2-phenylethyl)carbamothioyl]-L-cysteinylglycine, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (7 entities in total)
• Functional Keywords: gst, peitc, glutathione adduct, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : P09211
• Total number of polymer chains: 2
• Total formula weight: 48679.05

Authors

Kumari, V.,Ji, X. (deposition date: 2016-04-15, release date: 2016-10-12, Last modification date: 2023-09-27)

• Primary citation: Kumari, V.,Dyba, M.A.,Holland, R.J.,Liang, Y.H.,Singh, S.V.,Ji, X.; Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical.; Plos One, 11:e0163821-e0163821, 2016; PubMed: 27684484; DOI: 10.1371/journal.pone.0163821

Experimental method

X-RAY DIFFRACTION (1.945 Å)