5JAM

Yersinia pestis FabV variant T276V

Summary for 5JAM

• Entry DOI: 10.2210/pdb5jam/pdb
• Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: fatty acid biosynthesis fabv, oxidoreductase
• Biological source: Yersinia pestis
• Total number of polymer chains: 1
• Total formula weight: 45101.70

Authors

Pschibul, A.,Kuper, J.,HIrschbeck, M.,Kisker, C. (deposition date: 2016-04-12, release date: 2016-05-25, Last modification date: 2024-01-10)

• Primary citation: Neckles, C.,Pschibul, A.,Lai, C.T.,Hirschbeck, M.,Kuper, J.,Davoodi, S.,Zou, J.,Liu, N.,Pan, P.,Shah, S.,Daryaee, F.,Bommineni, G.R.,Lai, C.,Simmerling, C.,Kisker, C.,Tonge, P.J.; Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.; Biochemistry, 55:2992-3006, 2016; PubMed: 27136302; DOI: 10.1021/acs.biochem.5b01301

Experimental method

X-RAY DIFFRACTION (2 Å)