5J75
Fluorogen Activating Protein AM2.2 in complex with ML342
Summary for 5J75
Entry DOI | 10.2210/pdb5j75/pdb |
Related | 5J74 |
Descriptor | scFv AM2.2, PHOSPHATE ION, N,4-dimethyl-N-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}benzene-1-sulfonamide, ... (4 entities in total) |
Functional Keywords | fluorogen activating protein, drug discovery, biosensor, protein trafficking, immune system |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 55672.43 |
Authors | Stanfield, R.L.,Wilson, I.A.,Wu, Y. (deposition date: 2016-04-05, release date: 2016-05-04, Last modification date: 2023-09-27) |
Primary citation | Wu, Y.,Stauffer, S.R.,Stanfield, R.L.,Tapia, P.H.,Ursu, O.,Fisher, G.W.,Szent-Gyorgyi, C.,Evangelisti, A.,Waller, A.,Strouse, J.J.,Carter, M.B.,Bologa, C.,Gouveia, K.,Poslusney, M.,Waggoner, A.S.,Lindsley, C.W.,Jarvik, J.W.,Sklar, L.A. Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. J Biomol Screen, 21:74-87, 2016 Cited by PubMed: 26442911DOI: 10.1177/1087057115609145 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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