5J5Z

Crystal structure of the D444V disease-causing mutant of the human dihydrolipoamide dehydrogenase

5J5Z の概要

• エントリーDOI: 10.2210/pdb5j5z/pdb
• 分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: dihydrolipoamide dehydrogenase, e3 subunit, disease-causing mutant, e3 deficiency, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 107279.75

構造登録者

Szabo, E.,Mizsei, R.,Zambo, Z.,Torocsik, B.,Weiss, M.S.,Adam-Vizi, V.,Ambrus, A. (登録日: 2016-04-04, 公開日: 2017-11-15, 最終更新日: 2024-01-10)

• 主引用文献: Szabo, E.,Mizsei, R.,Wilk, P.,Zambo, Z.,Torocsik, B.,Weiss, M.S.,Adam-Vizi, V.,Ambrus, A.; Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase.; Free Radic. Biol. Med., 124:214-220, 2018; PubMed: 29908278; DOI: 10.1016/j.freeradbiomed.2018.06.008

実験手法

X-RAY DIFFRACTION (1.84 Å)