5J5J

Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5

5J5J の概要

• エントリーDOI: 10.2210/pdb5j5j/pdb
• 分子名称: Desmocollin-2,Desmoglein-2, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: extracellular cadherin domain, cell adhesion, desmosome, cell surface
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 67147.26

構造登録者

Brasch, J.,Harrison, O.J.,Shapiro, L. (登録日: 2016-04-02, 公開日: 2016-06-22, 最終更新日: 2023-09-27)

• 主引用文献: Harrison, O.J.,Brasch, J.,Lasso, G.,Katsamba, P.S.,Ahlsen, G.,Honig, B.,Shapiro, L.; Structural basis of adhesive binding by desmocollins and desmogleins.; Proc.Natl.Acad.Sci.USA, 113:7160-7165, 2016; PubMed: 27298358; DOI: 10.1073/pnas.1606272113

実験手法

X-RAY DIFFRACTION (3.29 Å)