5J5D

Crystal structure of Dihydrodipicolinate Synthase from Mycobacterium tuberculosis in complex with alpha-ketopimelic acid

5J5D の概要

• エントリーDOI: 10.2210/pdb5j5d/pdb
• 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, SODIUM ION, 2-oxoheptanedioic acid, ... (4 entities in total)
• 機能のキーワード: dap pathway, l-lysine, alpha-ketopimelic acid, lyase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• 細胞内の位置: Cytoplasm : P9WP25
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31108.35

構造登録者

Navratna, V.,Gopal, B. (登録日: 2016-04-02, 公開日: 2016-08-17, 最終更新日: 2023-11-08)

• 主引用文献: Shrivastava, P.,Navratna, V.,Silla, Y.,Dewangan, R.P.,Pramanik, A.,Chaudhary, S.,Rayasam, G.,Kumar, A.,Gopal, B.,Ramachandran, S.; Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues; Sci Rep, 6:30827-30827, 2016; PubMed: 27501775; DOI: 10.1038/srep30827

実験手法

X-RAY DIFFRACTION (2.4 Å)