5J23

Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in complex with 2'-phospho-ADP-ribose

Summary for 5J23

• Entry DOI: 10.2210/pdb5j23/pdb
• Descriptor: 2-hydroxyacid dehydrogenase, ACETATE ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: 2-hydroxyacid dehydrogenase, nadp, nysgrc, structural genomics, psi-biology, new york structural genomics research consortium, oxidoreductase
• Biological source: Rhizobium meliloti (strain 1021) (Ensifer meliloti)
• Total number of polymer chains: 4
• Total formula weight: 140416.47

Authors

Shabalin, I.G.,Gasiorowska, O.A.,Handing, K.B.,Bonanno, J.,Kutner, J.,Almo, S.C.,Minor, W.,New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2016-03-29, release date: 2016-04-13, Last modification date: 2023-09-27)

• Primary citation: Kutner, J.,Shabalin, I.G.,Matelska, D.,Handing, K.B.,Gasiorowska, O.,Sroka, P.,Gorna, M.W.,Ginalski, K.,Wozniak, K.,Minor, W.; Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies.; Biochemistry, 57:963-977, 2018; PubMed: 29309127; DOI: 10.1021/acs.biochem.7b01137

Experimental method

X-RAY DIFFRACTION (2.3 Å)