5IZR
Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate inhibitor and Terbium Chloride
Summary for 5IZR
Entry DOI | 10.2210/pdb5izr/pdb |
Related | 5IXC 5IZ5 |
Descriptor | Cytosolic phospholipase A2 delta, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate, TERBIUM(III) ION, ... (4 entities in total) |
Functional Keywords | signal transduction, phospholipase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytosol: Q86XP0 |
Total number of polymer chains | 4 |
Total formula weight | 369538.87 |
Authors | Wang, H.,Klein, M.G. (deposition date: 2016-03-25, release date: 2016-06-08, Last modification date: 2016-06-22) |
Primary citation | Wang, H.,Klein, M.G.,Snell, G.,Lane, W.,Zou, H.,Levin, I.,Li, K.,Sang, B.C. Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition. J.Mol.Biol., 428:2769-2779, 2016 Cited by PubMed: 27220631DOI: 10.1016/j.jmb.2016.05.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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