5IZL

The crystal structure of human eEFSec in complex with GDPCP

Summary for 5IZL

Entry DOI	10.2210/pdb5izl/pdb
Related	5IZK 5IZM
Descriptor	Selenocysteine-specific elongation factor, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (4 entities in total)
Functional Keywords	elongation factor, selenocysteine, selenocysteine trna, translation, gtpase, gdpcp, gtp
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	136218.95
Authors	Dobosz-Bartoszek, M.,Simonovic, M. (deposition date: 2016-03-25, release date: 2016-10-12, Last modification date: 2023-09-27)
Primary citation	Dobosz-Bartoszek, M.,Pinkerton, M.H.,Otwinowski, Z.,Chakravarthy, S.,Soll, D.,Copeland, P.R.,Simonovic, M. Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation. Nat Commun, 7:12941-12941, 2016 Cited by PubMed: 27708257 DOI: 10.1038/ncomms12941 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.72 Å)

Structure validation