5IXJ

Tryptophan Synthase beta-subunit from Pyrococcus furiosus with L-threonine non-covalently bound in the active site

Summary for 5IXJ

Entry DOI	10.2210/pdb5ixj/pdb
Descriptor	Tryptophan synthase beta chain 1, THREONINE, SODIUM ION, ... (4 entities in total)
Functional Keywords	substrate analog, lyase, plp, fold-type ii
Biological source	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Total number of polymer chains	4
Total formula weight	176108.62
Authors	Buller, A.R.,Herger, M.,Arnold, F.H. (deposition date: 2016-03-23, release date: 2016-08-17, Last modification date: 2023-11-15)
Primary citation	Herger, M.,van Roye, P.,Romney, D.K.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H. Synthesis of beta-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase. J.Am.Chem.Soc., 138:8388-8391, 2016 Cited by PubMed: 27355405 DOI: 10.1021/jacs.6b04836 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation