5IXB
Structure of human Melanoma Inhibitory Activity (MIA) Protein in complex with Pyrimidin-2-amine
Summary for 5IXB
Entry DOI | 10.2210/pdb5ixb/pdb |
Descriptor | Melanoma-derived growth regulatory protein, PYRIMIDIN-2-AMINE, ACETATE ION, ... (4 entities in total) |
Functional Keywords | all beta, sh3 domain-like fold, extracellular, cell adhesion |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: Q16674 |
Total number of polymer chains | 2 |
Total formula weight | 24824.57 |
Authors | Yip, K.T.,Gasper, R.,Zhong, X.Y.,Seibel, N.,Puetz, S.,Autzen, J.,Scherkenbeck, J.,Hofmann, E.,Stoll, R. (deposition date: 2016-03-23, release date: 2016-08-17, Last modification date: 2024-01-10) |
Primary citation | Yip, K.T.,Zhong, X.Y.,Seibel, N.,Putz, S.,Autzen, J.,Gasper, R.,Hofmann, E.,Scherkenbeck, J.,Stoll, R. Small Molecules Antagonise the MIA-Fibronectin Interaction in Malignant Melanoma. Sci Rep, 6:25119-25119, 2016 Cited by PubMed: 27151361DOI: 10.1038/srep25119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.39 Å) |
Structure validation
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