5IUC

Crystal structure of the GspB siglec domain with sialyl T antigen bound

Replaces:  4I8EReplaces:  3QD1

Summary for 5IUC

• Entry DOI: 10.2210/pdb5iuc/pdb
• Related: 3QC5 3QC6
• Descriptor: Platelet binding protein GspB, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: bacterial adhesin, lectin, immunoglobulin fold, serine-rich repeat, sugar binding protein
• Biological source: Streptococcus gordonii
• Total number of polymer chains: 2
• Total formula weight: 29302.60

Authors

Loukachevitch, L.V.,Fialkowski, K.P.,Wawrzak, Z.,Iverson, T.M. (deposition date: 2016-03-17, release date: 2016-04-13, Last modification date: 2023-09-27)

• Primary citation: Pyburn, T.M.,Bensing, B.A.,Xiong, Y.Q.,Melancon, B.J.,Tomasiak, T.M.,Ward, N.J.,Yankovskaya, V.,Oliver, K.M.,Cecchini, G.,Sulikowski, G.A.,Tyska, M.J.,Sullam, P.M.,Iverson, T.M.; A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors.; PLoS Pathog., 7:e1002112-, 2011; PubMed: 21765814; DOI: 10.1371/journal.ppat.1002112

Experimental method

X-RAY DIFFRACTION (1.253 Å)