5IIN
Crystal structure of the pre-catalytic ternary extension complex of DNA polymerase lambda with an 8-oxo-dG:dC base-pair
Summary for 5IIN
Entry DOI | 10.2210/pdb5iin/pdb |
Related | 5III 5IIJ 5IIK 5IIL 5IIM 5IIO |
Descriptor | DNA polymerase lambda, DNA (5'-D(P*GP*CP*CP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... (8 entities in total) |
Functional Keywords | transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q9UGP5 |
Total number of polymer chains | 4 |
Total formula weight | 44238.26 |
Authors | Burak, M.J.,Guja, K.E.,Garcia-Diaz, M. (deposition date: 2016-03-01, release date: 2016-08-17, Last modification date: 2024-03-06) |
Primary citation | Burak, M.J.,Guja, K.E.,Hambardjieva, E.,Derkunt, B.,Garcia-Diaz, M. A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG. Embo J., 35:2045-2059, 2016 Cited by PubMed: 27481934DOI: 10.15252/embj.201694332 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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