5IIA

Crystal structure of red abalone egg VERL repeat 3 in complex with sperm lysin at 1.7 A resolution (crystal form I)

5IIA の概要

• エントリーDOI: 10.2210/pdb5iia/pdb
• 関連するPDBエントリー: 1LIS 1LYN 2LIS 2LYN 3D4C 3D4G 3EF7 3NK3 3NK4 5II4 5II5 5II7 5II8 5II9 5IIB 5IIC
• 分子名称: Egg-lysin, Vitelline envelope sperm lysin receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: cell adhesion, fertilization, egg-sperm interaction, gamete recognition, sperm receptor, egg coat, vitelline envelope, zp domain, zp-n domain, sperm acrosome, egg coat penetration
• 由来する生物種: Haliotis rufescens (California red abalone); 詳細
• 細胞内の位置: Cytoplasmic vesicle, secretory vesicle, acrosome lumen : P04552; Cell membrane ; Single-pass membrane protein : Q8WR62
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 125188.65

構造登録者

Sadat Al-Hosseini, H.,Raj, I.,Nishimura, K.,De Sanctis, D.,Jovine, L. (登録日: 2016-03-01, 公開日: 2017-06-14, 最終更新日: 2024-01-10)

• 主引用文献: Raj, I.,Sadat Al Hosseini, H.,Dioguardi, E.,Nishimura, K.,Han, L.,Villa, A.,de Sanctis, D.,Jovine, L.; Structural Basis of Egg Coat-Sperm Recognition at Fertilization.; Cell, 169:1315-1326.e17, 2017; PubMed: 28622512; DOI: 10.1016/j.cell.2017.05.033

実験手法

X-RAY DIFFRACTION (1.7 Å)