5IH2

Structure, thermodynamics, and the role of conformational dynamics in the interactions between the N-terminal SH3 domain of CrkII and proline-rich motifs in cAbl

5IH2 の概要

• エントリーDOI: 10.2210/pdb5ih2/pdb
• 分子名称: Adapter molecule crk, Proline rich Peptide, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• 機能のキーワード: sh3 domain polyproline ii motif, signaling protein
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Cytoplasm : Q64010
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 17037.12

構造登録者

Bhatt, V.S.,Zeng, D.,Krieger, I.,Sacchettini, J.C.,Cho, J.-H. (登録日: 2016-02-28, 公開日: 2016-06-29, 最終更新日: 2023-09-27)

• 主引用文献: Bhatt, V.S.,Zeng, D.,Krieger, I.,Sacchettini, J.C.,Cho, J.H.; Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl.; Biophys.J., 110:2630-2641, 2016; PubMed: 27332121; DOI: 10.1016/j.bpj.2016.05.008

実験手法

X-RAY DIFFRACTION (1.8 Å)