5IFR

Structure of the stable UBE2D3-UbDha conjugate

Summary for 5IFR

• Entry DOI: 10.2210/pdb5ifr/pdb
• Descriptor: Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B, GLYCEROL, ... (4 entities in total)
• Functional Keywords: ubiquitin conjugate, dehydroalanine, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 25669.35

Authors

Pruneda, J.N.,Mulder, M.P.C.,Witting, K.,Ovaa, H.,Komander, D. (deposition date: 2016-02-26, release date: 2016-05-11, Last modification date: 2024-01-10)

• Primary citation: Mulder, M.P.,Witting, K.,Berlin, I.,Pruneda, J.N.,Wu, K.P.,Chang, J.G.,Merkx, R.,Bialas, J.,Groettrup, M.,Vertegaal, A.C.,Schulman, B.A.,Komander, D.,Neefjes, J.,El Oualid, F.,Ovaa, H.; A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.; Nat.Chem.Biol., 12:523-530, 2016; PubMed: 27182664; DOI: 10.1038/nchembio.2084

Experimental method

X-RAY DIFFRACTION (2.2 Å)