5IEG

Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin.

5IEG の概要

• エントリーDOI: 10.2210/pdb5ieg/pdb
• 関連するPDBエントリー: 5F0E 5H9O 5HJO 5HJR 5IED 5IEE 5IEF
• 分子名称: Neutral alpha-glucosidase AB, Glucosidase 2 subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: enzyme glycosyl hydrolase gh31 quality control exoglycosidase, hydrolase, mon-dnj
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Endoplasmic reticulum : Q8BHN3 O08795
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 116231.52

構造登録者

Caputo, A.T.,Roversi, P.,Alonzi, D.S.,Kiappes, J.L.,Zitzmann, N. (登録日: 2016-02-25, 公開日: 2016-07-27, 最終更新日: 2024-04-24)

• 主引用文献: Caputo, A.T.,Alonzi, D.S.,Marti, L.,Reca, I.B.,Kiappes, J.L.,Struwe, W.B.,Cross, A.,Basu, S.,Lowe, E.D.,Darlot, B.,Santino, A.,Roversi, P.,Zitzmann, N.; Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.; Proc.Natl.Acad.Sci.USA, 113:E4630-E4638, 2016; PubMed: 27462106; DOI: 10.1073/pnas.1604463113

実験手法

X-RAY DIFFRACTION (1.822 Å)