5IDL

Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8

5IDL の概要

• エントリーDOI: 10.2210/pdb5idl/pdb
• 分子名称: Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• 機能のキーワード: hiv env, germline-targeting immunogen, viral protein
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20173.57

構造登録者

Julien, J.P.,Ereno-Orbea, J.,Jardine, J.G.,Schief, W.R.,Wilson, I.A. (登録日: 2016-02-24, 公開日: 2016-10-05, 最終更新日: 2023-09-27)

• 主引用文献: Jardine, J.G.,Kulp, D.W.,Havenar-Daughton, C.,Sarkar, A.,Briney, B.,Sok, D.,Sesterhenn, F.,Ereno-Orbea, J.,Kalyuzhniy, O.,Deresa, I.,Hu, X.,Spencer, S.,Jones, M.,Georgeson, E.,Adachi, Y.,Kubitz, M.,deCamp, A.C.,Julien, J.P.,Wilson, I.A.,Burton, D.R.,Crotty, S.,Schief, W.R.; HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.; Science, 351:1458-1463, 2016; PubMed: 27013733; DOI: 10.1126/science.aad9195

実験手法

X-RAY DIFFRACTION (2.9 Å)