5ID2

Asymmetry in the active site of Mycobacterium tuberculosis AhpE upon exposure to Mycothiol

5ID2 の概要

• エントリーDOI: 10.2210/pdb5id2/pdb
• 分子名称: Putative peroxiredoxin Rv2238c, GLYCEROL, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: thioredoxin fold, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis H37Rv; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 73277.82

構造登録者

Kumar, A.,Balakrishna, A.M.,Gruber, G. (登録日: 2016-02-23, 公開日: 2016-08-03, 最終更新日: 2023-11-15)

• 主引用文献: Kumar, A.,Balakrishna, A.M.,Nartey, W.,Manimekalai, M.S.S.,Gruber, G.; Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive pathway of AhpE via mycothiol; Free Radic. Biol. Med., 97:588-601, 2016; PubMed: 27417938; DOI: 10.1016/j.freeradbiomed.2016.07.007

実験手法

X-RAY DIFFRACTION (2.43 Å)