5ICE

Crystal structure of (S)-norcoclaurine 6-O-methyltransferase with S-adenosyl-L-homocysteine and norlaudanosoline

5ICE の概要

• エントリーDOI: 10.2210/pdb5ice/pdb
• 分子名称: (S)-norcoclaurine 6-O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, (1S)-1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol, ... (6 entities in total)
• 機能のキーワード: methyltransferase, benzylisoquinoline alkaloid, transferase
• 由来する生物種: Thalictrum flavum subsp. glaucum (Yellow meadow rue)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40631.01

構造登録者

Robin, A.Y.,Graindorge, M.,Giustini, C.,Dumas, R.,Matringe, M. (登録日: 2016-02-23, 公開日: 2016-06-08, 最終更新日: 2016-10-12)

• 主引用文献: Robin, A.Y.,Giustini, C.,Graindorge, M.,Matringe, M.,Dumas, R.; Crystal structure of norcoclaurine-6-O-methyltransferase, a key rate-limiting step in the synthesis of benzylisoquinoline alkaloids.; Plant J., 87:641-653, 2016; PubMed: 27232113; DOI: 10.1111/tpj.13225

実験手法

X-RAY DIFFRACTION (1.6 Å)