5IBN
Ultra high resolution crystal structure of the apo- form of second bromodomain of BRD2.
Summary for 5IBN
Entry DOI | 10.2210/pdb5ibn/pdb |
Descriptor | Bromodomain-containing protein 2, CHLORIDE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | bet-family, acetyl-lysine binding, transcription |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : P25440 |
Total number of polymer chains | 1 |
Total formula weight | 13849.23 |
Authors | Tripathi, S.K.,Padmanabhan, B. (deposition date: 2016-02-22, release date: 2016-06-22, Last modification date: 2023-11-08) |
Primary citation | Tripathi, S.,Mathur, S.,Deshmukh, P.,Manjula, R.,Padmanabhan, B. A Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the Complex Plos One, 11:e0156344-e0156344, 2016 Cited by PubMed: 27243809DOI: 10.1371/journal.pone.0156344 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.94 Å) |
Structure validation
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