5IA9
The structure of microsomal glutathione transferase 1 in complex with Meisenheimer complex
Summary for 5IA9
Entry DOI | 10.2210/pdb5ia9/pdb |
EMDB information | 8084 |
Descriptor | Microsomal glutathione S-transferase 1, 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (4 entities in total) |
Functional Keywords | membrane, enzyme, meisenheimer complex, transferase |
Biological source | Rattus norvegicus (Norway Rat) |
Cellular location | Microsome: P08011 |
Total number of polymer chains | 1 |
Total formula weight | 20106.05 |
Authors | Kuang, Q.,Purhonen, P.,Jegerschold, C.,Morgenstern, R.,Hebert, H. (deposition date: 2016-02-21, release date: 2017-07-12, Last modification date: 2017-08-23) |
Primary citation | Kuang, Q.,Purhonen, P.,Alander, J.,Svensson, R.,Hoogland, V.,Winerdal, J.,Spahiu, L.,Ottosson-Wadlund, A.,Jegerschold, C.,Morgenstern, R.,Hebert, H. Dead-end complex, lipid interactions and catalytic mechanism of microsomal glutathione transferase 1, an electron crystallography and mutagenesis investigation. Sci Rep, 7:7897-7897, 2017 Cited by PubMed: 28801553DOI: 10.1038/s41598-017-07912-3 PDB entries with the same primary citation |
Experimental method | ELECTRON CRYSTALLOGRAPHY (3.5 Å) |
Structure validation
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