5I8E
Crystal Structure of Broadly Neutralizing HIV-1 Fusion Peptide-Targeting Antibody VRC34.01 Fab
Summary for 5I8E
Entry DOI | 10.2210/pdb5i8e/pdb |
Related | 5I8C 5I8H |
Descriptor | VRC34.01 Fab heavy chain, VRC34.01 Fab light chain, ZINC ION, ... (4 entities in total) |
Functional Keywords | hiv-1, envelope, trimer, fusion peptide, antibody, neutralizing, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 93751.99 |
Authors | Xu, K.,Zhou, T.,Liu, K.,Kwong, P.D. (deposition date: 2016-02-18, release date: 2016-05-25, Last modification date: 2023-09-27) |
Primary citation | Kong, R.,Xu, K.,Zhou, T.,Acharya, P.,Lemmin, T.,Liu, K.,Ozorowski, G.,Soto, C.,Taft, J.D.,Bailer, R.T.,Cale, E.M.,Chen, L.,Choi, C.W.,Chuang, G.Y.,Doria-Rose, N.A.,Druz, A.,Georgiev, I.S.,Gorman, J.,Huang, J.,Joyce, M.G.,Louder, M.K.,Ma, X.,McKee, K.,O'Dell, S.,Pancera, M.,Yang, Y.,Blanchard, S.C.,Mothes, W.,Burton, D.R.,Koff, W.C.,Connors, M.,Ward, A.B.,Kwong, P.D.,Mascola, J.R. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science, 352:828-833, 2016 Cited by PubMed: 27174988DOI: 10.1126/science.aae0474 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.655 Å) |
Structure validation
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