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5I7V

Crystal structure of B. pseudomallei FabI in complex with NAD and PT02

Summary for 5I7V
Entry DOI10.2210/pdb5i7v/pdb
DescriptorEnoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-phenoxy-5-propyl-phenol, ... (4 entities in total)
Functional Keywordsenoyl-acp reductase, burkholderia pseudomallei, diphenyl ethers, slow-binding inhibitors, oxidoreductase
Biological sourceBurkholderia pseudomallei
Total number of polymer chains3
Total formula weight90651.31
Authors
Hirschbeck, M.W.,Eltschkner, S.,Tonge, P.J.,Kisker, C. (deposition date: 2016-02-18, release date: 2017-02-22, Last modification date: 2024-01-10)
Primary citationNeckles, C.,Eltschkner, S.,Cummings, J.E.,Hirschbeck, M.,Daryaee, F.,Bommineni, G.R.,Zhang, Z.,Spagnuolo, L.,Yu, W.,Davoodi, S.,Slayden, R.A.,Kisker, C.,Tonge, P.J.
Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase.
Biochemistry, 56:1865-1878, 2017
Cited by
PubMed: 28225601
DOI: 10.1021/acs.biochem.6b01048
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

数据于2024-03-27公开中

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