5I3R

Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor

5I3R の概要

• エントリーDOI: 10.2210/pdb5i3r/pdb
• 関連するPDBエントリー: 4W9W 4W9X 5I3O
• 分子名称: BMP-2-inducible protein kinase, N-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1H-indazol-3-yl]cyclopropanecarboxamide, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69039.28

構造登録者

Counago, R.M.,Sorrell, F.J.,Krojer, T.,Savitsky, P.,Elkins, J.M.,Axtman, A.,Drewry, D.,Wells, C.,Zhang, C.,Zuercher, W.,Willson, T.M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Arruda, P.,Gileadi, O.,Structural Genomics Consortium (SGC) (登録日: 2016-02-10, 公開日: 2016-03-09, 最終更新日: 2023-09-27)

• 主引用文献: Counago, R.M.,Sorrell, F.J.,Krojer, T.,Elkins, J.M.,Gileadi, O.,Willson, T.M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Arruda, P.; Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)