5HZ5

FABP5 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-3-(1H-tetrazol-5-yl)-quinoline

Summary for 5HZ5

• Entry DOI: 10.2210/pdb5hz5/pdb
• Descriptor: Fatty acid-binding protein, epidermal, DIMETHYL SULFOXIDE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q01469
• Total number of polymer chains: 1
• Total formula weight: 15619.33

Authors

Ehler, A.,Rudolph, M.G. (deposition date: 2016-02-02, release date: 2017-01-25, Last modification date: 2017-10-11)

• Primary citation: Kuhne, H.,Obst-Sander, U.,Kuhn, B.,Conte, A.,Ceccarelli, S.M.,Neidhart, W.,Rudolph, M.G.,Ottaviani, G.,Gasser, R.,So, S.S.,Li, S.,Zhang, X.,Gao, L.,Myers, M.; Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.; Bioorg. Med. Chem. Lett., 26:5092-5097, 2016; PubMed: 27658368; DOI: 10.1016/j.bmcl.2016.08.071

Experimental method

X-RAY DIFFRACTION (1.4 Å)