5HWY

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 10 mM Na+ and zero Ca2+

5HWY の概要

• エントリーDOI: 10.2210/pdb5hwy/pdb
• 関連するPDBエントリー: 5HWX 5HXC 5HXE 5HXH 5HXR 5HXS 5HYA
• 分子名称: Uncharacterized membrane protein MJ0091, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, SODIUM ION, ... (7 entities in total)
• 機能のキーワード: na+/ca2+ exchange, calcium signalling, membrane transporter, induced conformational change, membrane protein
• 由来する生物種: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
• 細胞内の位置: Cell membrane ; Multi-pass membrane protein : Q57556
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35915.20

構造登録者

Liao, J.,Jiang, Y.X.,Faraldo-Gomez, J.D. (登録日: 2016-01-29, 公開日: 2016-05-18, 最終更新日: 2023-11-08)

• 主引用文献: Liao, J.,Marinelli, F.,Lee, C.,Huang, Y.,Faraldo-Gomez, J.D.,Jiang, Y.; Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger; Nat.Struct.Mol.Biol., 23:590-599, 2016; PubMed: 27183196; DOI: 10.1038/nsmb.3230

実験手法

X-RAY DIFFRACTION (2.098 Å)