5HW8

Candida albicans FKBP12 P104G protein bound with FK506 in C2 space group

Summary for 5HW8

• Entry DOI: 10.2210/pdb5hw8/pdb
• Related: 5HTG 5HW6 5HW7
• Descriptor: FK506-binding protein 1, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total)
• Functional Keywords: fkbp12, prolyl isomerase, fk506, isomerase
• Biological source: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
• Cellular location: Cytoplasm: P28870
• Total number of polymer chains: 8
• Total formula weight: 110614.01

Authors

Tonthat, N.K.,Schumacher, M.A. (deposition date: 2016-01-28, release date: 2016-09-14, Last modification date: 2024-03-06)

• Primary citation: Tonthat, N.K.,Juvvadi, P.R.,Zhang, H.,Lee, S.C.,Venters, R.,Spicer, L.,Steinbach, W.J.,Heitman, J.,Schumacher, M.A.; Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.; Mbio, 7:e00492-e00416, 2016; PubMed: 27118592; DOI: 10.1128/mBio.00492-16

Experimental method

X-RAY DIFFRACTION (2.86 Å)