5HVJ

Crystal structure of LIMK1 D460N mutant in complex with AMP-PNP

Summary for 5HVJ

• Entry DOI: 10.2210/pdb5hvj/pdb
• Related: 5HVK
• Descriptor: LIM domain kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total)
• Functional Keywords: kinase atp analog actin-remodeling, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 73292.62

Authors

Hamill, S.,Boggon, T.J. (deposition date: 2016-01-28, release date: 2016-05-04, Last modification date: 2023-09-27)

• Primary citation: Hamill, S.,Lou, H.J.,Turk, B.E.,Boggon, T.J.; Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.; Mol.Cell, 62:397-408, 2016; PubMed: 27153537; DOI: 10.1016/j.molcel.2016.04.001

Experimental method

X-RAY DIFFRACTION (2.2 Å)