5HUU
Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate
Summary for 5HUU
Entry DOI | 10.2210/pdb5huu/pdb |
Related | 5HUS 5HUT 5HUV |
Descriptor | Alpha,alpha-trehalose-phosphate synthase [UDP-forming], URIDINE-5'-DIPHOSPHATE, 6-O-phosphono-alpha-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | trehalose-6-phosphate synthase, transferase |
Biological source | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Total number of polymer chains | 2 |
Total formula weight | 110370.94 |
Authors | Miao, Y.,Brennan, R.G. (deposition date: 2016-01-27, release date: 2017-05-03, Last modification date: 2024-04-03) |
Primary citation | Miao, Y.,Tenor, J.L.,Toffaletti, D.L.,Maskarinec, S.A.,Liu, J.,Lee, R.E.,Perfect, J.R.,Brennan, R.G. Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design. MBio, 8:-, 2017 Cited by PubMed: 28743811DOI: 10.1128/mBio.00643-17 PDB entries with the same primary citation |
Experimental method |
Structure validation
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