5HPN

A circularly permuted PduA forming an icosahedral cage

5HPN の概要

• エントリーDOI: 10.2210/pdb5hpn/pdb
• 分子名称: Permuted PduA, SULFATE ION (3 entities in total)
• 機能のキーワード: pdua, protein design, icosahedron, cage, bmc, mcp, microcompartment, design, de novo protein
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 43986.36

構造登録者

Leibly, D.J.,Jorda, J.,Yeates, T.O. (登録日: 2016-01-20, 公開日: 2016-04-06, 最終更新日: 2023-09-27)

主引用文献

Jorda, J.,Leibly, D.J.,Thompson, M.C.,Yeates, T.O.
Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein.
Chem.Commun.(Camb.), 52:5041-5044, 2016

PubMed Abstract: We report the crystal structure of a novel 60-subunit dodecahedral cage that results from self-assembly of a re-engineered version of a natural protein (PduA) from the Pdu microcompartment shell. Biophysical data illustrate the dependence of assembly on solution conditions, opening up new applications in microcompartment studies and nanotechnology.

PubMed: 26988700
DOI: 10.1039/c6cc00851h

実験手法

X-RAY DIFFRACTION (2.509 Å)