5HPL

System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: Rsp5 and UbV R5.4

Summary for 5HPL

Entry DOI	10.2210/pdb5hpl/pdb
Related	5HPK 5HPS 5HPT
Descriptor	Rsp5, Ubiquitin variant R5.4 (3 entities in total)
Functional Keywords	hect e3, rsp5, ubiquitin, ubv, ligase
Biological source	Saccharomyces cerevisiae More
Total number of polymer chains	4
Total formula weight	109481.94
Authors	Wu, K.-P.,Kamadurai, H.B.,Schulman, B.A. (deposition date: 2016-01-20, release date: 2016-03-16, Last modification date: 2023-09-27)
Primary citation	Zhang, W.,Wu, K.P.,Sartori, M.A.,Kamadurai, H.B.,Ordureau, A.,Jiang, C.,Mercredi, P.Y.,Murchie, R.,Hu, J.,Persaud, A.,Mukherjee, M.,Li, N.,Doye, A.,Walker, J.R.,Sheng, Y.,Hao, Z.,Li, Y.,Brown, K.R.,Lemichez, E.,Chen, J.,Tong, Y.,Harper, J.W.,Moffat, J.,Rotin, D.,Schulman, B.A.,Sidhu, S.S. System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62:121-136, 2016 Cited by PubMed: 26949039 DOI: 10.1016/j.molcel.2016.02.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation