5HL7

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin

Summary for 5HL7

Entry DOI	10.2210/pdb5hl7/pdb
Related	4WCE 4WF9 4WFA 4WFB
Descriptor	50S ribosomal protein L2, 50S ribosomal protein L15, 50S ribosomal protein L16, ... (35 entities in total)
Functional Keywords	ribosome, lefamulin, rna, antibiotic
Biological source	Staphylococcus aureus subsp. aureus NCTC 8325 More
Total number of polymer chains	28
Total formula weight	1365458.03
Authors	Eyal, Z.,Matzov, D.,Krupkin, M.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A. (deposition date: 2016-01-14, release date: 2016-12-21, Last modification date: 2024-01-10)
Primary citation	Eyal, Z.,Matzov, D.,Krupkin, M.,Paukner, S.,Riedl, R.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A. A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism. Sci Rep, 6:39004-39004, 2016 Cited by PubMed: 27958389 DOI: 10.1038/srep39004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.55 Å)

Structure validation