5HKZ
Crystal Structure of c-Cbl TKBD in complex with SPRY2 peptide (36-60, pY55) Refined to 1.8 A Resolution (P21 form)
Summary for 5HKZ
Entry DOI | 10.2210/pdb5hkz/pdb |
Related | 5HKW 5HKX 5HKY 5HL0 |
Descriptor | E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2, SODIUM ION, ... (4 entities in total) |
Functional Keywords | spry2, cbl, protein-protein interaction, anticancer target, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 38717.38 |
Authors | Lovell, S.,Battaile, K.P.,Mehzabeen, N.,Zhang, N.,Cooper, A.,Gao, P.,Perez, R.P. (deposition date: 2016-01-14, release date: 2017-01-18, Last modification date: 2023-11-15) |
Primary citation | Zhang, N.,Ferris, D.,Lovell, S.,Smalter-Hall, A.,Battaile, K.P.,Anbanandam, A.,Gao, P.,Hanzlik, R.,Perez, R.P. Crystal Structure of c-Cbl TKBD in complex with SPRY2 peptide (36-60, pY55) Refined to 1.8 A Resolution (P21 form) To be published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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