5HHG

Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex

Summary for 5HHG

Entry DOI	10.2210/pdb5hhg/pdb
Descriptor	RNA-directed RNA polymerase NS5, Importin subunit alpha-1 (3 entities in total)
Functional Keywords	dengue, ns5, importin, protein transport-viral protein complex, protein transport/viral protein
Biological source	Dengue virus type 2 (strain Puerto Rico/PR159-S1/1969) (DENV-2) More
Total number of polymer chains	2
Total formula weight	50596.78
Authors	Smith, K.M.,Forwood, J.K. (deposition date: 2016-01-11, release date: 2016-05-18, Last modification date: 2024-03-06)
Primary citation	Tay, M.Y.,Smith, K.,Ng, I.H.,Chan, K.W.,Zhao, Y.,Ooi, E.E.,Lescar, J.,Luo, D.,Jans, D.A.,Forwood, J.K.,Vasudevan, S.G. The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12:e1005886-e1005886, 2016 Cited by PubMed: 27622521 DOI: 10.1371/journal.ppat.1005886 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation